Transmission dengue virus can be transmitted from the bite of an infected aedes mosquito. A risk to anyone traveling to a tropical or subtropical region of the world where dengue virus is found. Abstract dengue virus denv is responsible for the clinical entity known as dengue that is a great concern for economy and public health of tropical countries. It is clinically manifested as a subclinical infection, with undifferentiated fever the socalled dengue fever, and in a small number of individuals the dengue hemorrhagic fever dengue shock syndrome. Each denv has four or more genetic groups or genotypes. The disease is caused by four serologically and genetically distinct viruses termed dengue virus denv 1, 2, 3 and 4. Molecular cloning methods have led to a greater understanding of the structure of the rna genome and definition of virusspecific structural and nonstructural proteins. Respuesta inmune e inmunopatogenesis en las infecciones con. When their distribution is combined with rapid population growth, unplanned urbanization, and increased international travel, extensive transmission of denv is likely in africa figure 2,4.
Dengue fever can be caused by any one of four types of dengue virus. This flavivirus is a single strand rna virus that after their translation and replication in host cells produces three structural and seven nonstructural proteins with specific function in. Dengue virus denv is responsible for the clinical entity known as dengue that is a great concern for economy and public health of tropical countries. Africa and can serve as vectors of dengue virus denv.
Four distinct serotypes of the dengue virus dengue1, dengue2, dengue3, and dengue4 exist, with numerous virus strains found worldwide. Dengue is among the most important mosquitoborne viral disease in the world. Dengue is likely underrecognized and underreported in africa because of low awareness by health care providers, other prevalent febrile illnesses, and lack of diagnostic testing. Each year, an estimated 390 million people are infected. This flavivirus is a single strand rna virus that after their translation and replication in host cells produces three structural. Need to strengthen the molecular surveillance in peru. Virus del dengue o 19 hv xq yluxv lfrvdhgur gh qp dsurl. You can be infected by at least two if not all four types at different times during your lifetime, but only once by the same type. Molecular cloning methods have led to a greater understanding of the structure of the rna genome and definition of virus specific structural and nonstructural proteins. The new clinical classifications are dengue and severe dengue. Over the past 5 decades, cases of epidemic or sporadic dengue have been reported in many countries.